Dr. Manoj Balakrishna Menon
Assistant Professor,
Kusuma School of Biological Sciences
Indian Insitute of Technology Delhi
New Delhi, India
Research Interests
Protein kinases & Cell Signaling,
Cell Death pathways,
Cytoskeleton and Autophagy...
Education
2018 Habilitation in Biochemistry
Hannover Medical School, Germany
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2010 PhD Molecular Medicine
HBRS, Hannover Medical School, Germany (Prof. Dr. M. Gaestel / Dr. A. Kotlyarov)
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2006 MSc Microbial Gene Technology
Madurai Kamaraj University, India
(Prof. Dr. S. Shanmuga Sundaram)
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2004 BSc Biotechnology
Presidency College, Bangalore University
Bengaluru, India
Experience
Assistant Professor, KSBS, IIT Delhi
From May 2019 onwards
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Privatdozent (Adjunct Faculty)
Hannover Medical School, Germany
Dec 2018 - April 2019
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Guest Researcher, NUS, Singapore
(Prof. Dr. David Engelberg)
Aug 2015 - Oct 2015
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Post-doctoral Staff Scientist
Cell Biochemistry, Hannover Medical School,
Germany (Prof. Dr. Matthias Gaestel)
June 2010 - April 2019
Other roles
Associate Editor, Frontiers in Cell Dev Biol - Since 2021
Academic Editor, Plos One - Since 2018
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Guest Associate Editor, Frontiers in Pharmacology
Research Topic: Autophagy & related Transcription Factors
in Liver & Gut diseases - 2018 - 2021
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Peer-review Board Member, Bio-Protocols, Since 2018
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Member, Signal Transduction Society, DE, From 2017
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Guest Associate Editor, Frontiers in Cell Dev Biology
Research Topic: Emerging Functions of Septins - 2016-18
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Member, Biochemical Society, UK, From 2015
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Review Editor, Frontiers in Cell Dev Biology, 2015- 2021
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Reviewer for journals including J Cell Science, Clini Sci,
Bioscience Rep, OncoTargets & Therapy, Cell Death Dis,
Res & Rep in Biochem etc.
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Awards & Achievements
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FITT Trailblazer Technology Transfer Award 2017-2022 - by Foundation for Innovation and Technology Transfer, IIT Delhi
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Sir Hans Krebs Prize 2018 - Germany-wide prize for basic biomedical research
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STS Science Award 2017- from Signal Transduction Society for work by a postdoc/junior PI.
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2017: Invited Speaker- EMBO conference on Molecular & Cellular Biology of Septins- Berlin, Oct 8-11.
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2015: Boehringer Ingelheim Fonds (BIF) Travel Grant for a research visit to NUS, Singapore.
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2012: Organizer’s Travel Grant to attend ‘’ Batsheva de Rothschild Seminar on the Biochemistry, Biology and Pathology of MAP Kinases’’, Jerusalem Hills, Israel.
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2009: HBRS Travel grant to attend ‘’ The EMBO Meeting 2009’’, Amsterdam, The Netherlands.
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2006: Doctoral fellowship, Molecular Medicine by the HBRS,Hannover, DE.
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2006: Qualified for Council for Scientific and Industrial Research (CSIR) junior research fellowship (JRF)
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2006: University first rank, MSc Microbial Gene Technology, Madurai Kamaraj University, Madurai, India.
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2005: ‘’Maveeran Sundaralingam scholarship’’, MKU, India.
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2004: ‘’Bharat Petroleum Scholarship for Higher Studies’’ by Bharat Petroleum Corporation, India.
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Selected Recent Publications
Chanchal Chauhan, Andreas Kraemer, Stefan Knapp, Mark Windheim, Alexey Kotlyarov, Manoj B. Menon*, Matthias Gaestel*. (2023). 5-iodotubercidin sensitizes cells to RIPK1-dependent necroptosis by interfering with NFκB signaling. Cell Death Discovery. In press. https://doi.org/10.1038/s41420-023-01576-x
Chanchal Chauhan, Ana Martinez Del Val, Rainer Niedenthal, Jesper Velgaard Olsen, Alexey Kotlyarov, Simon Bekker-Jensen, Matthias Gaestel*, Manoj B. Menon*. 2023. PRMT5-mediated regulatory arginine methylation of RIPK3. Cell Death Discovery. 9:14. https://doi.org/10.1038/s41420-023-01299-z
Menon MB*, Gropengießer J*, Fischer J, Novikova L, Deuretzbacher A, Lafera J, Schimmeck H, Czymmeck N, Ronkina N, Kotlyarov A, Aepfelbacher M, Gaestel M & Ruckdeschel K. 2017. p38MAPK/MK2-dependent phosphorylation controls cytotoxic RIPK1 signaling in inflammation and infection. Nat Cell Biol. 19: 1248–1259.
Abbey M, Hakim C, Anand R, Lafera J, Schambach A, Kispert A, Taft MH, Kaever V, Kotlyarov A, Gaestel M* and Menon MB*. 2016. GTPase domain driven dimerization of SEPT7 is dispensable for the critical role of septins in fibroblast cytokinesis. Scientific Reports.6:20007.
Menon MB, Dhamija S, Kotlyarov A and Gaestel M. 2015. The problem of pyridinyl imidazole class inhibitors of p38 MAPK in autophagy research. Autophagy. 11(8): 1425-27.
Menon MB*, Sawada A, Chaturvedi A, Mishra P, Schuster-Gossler K, Galla M, Schambach M, Gossler A, Förster R, Heuser M, Kotlyarov A, Kinoshita M* & Gaestel M*. 2014. Genetic deletion of SEPT7 reveals a cell type-specific role of septins in microtubule destabilization for the completion of cytokinesis. PLoS Genet. 10(8):e1004558.IF2013: 8.167
Menon MB* & Gaestel M. 2015. Sep(t)arate or not: how some cells take septin-independent routes through cytokinesis. J Cell Science. 128(10):1877-86. (Commentary).